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Yeast grown in continuous culture systems can detect mutagens with improved sensitivity relative to the Ames test

Continuous culture systems allow for the controlled growth of microorganisms over a long period of time. Here, we develop a novel test for mutagenicity that involves growing yeast in continuous culture systems exposed to low levels of mutagen for a period of approximately 20 days. In contrast, most...

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Detalles Bibliográficos
Autores principales: Ong, Joseph Y., Pence, Julia T., Molik, David C., Shepherd, Heather A. M., Goodson, Holly V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968628/
https://www.ncbi.nlm.nih.gov/pubmed/33730086
http://dx.doi.org/10.1371/journal.pone.0235303