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Extracellular matrix density regulates the formation of tumour spheroids through cell migration
In this work, we show how the mechanical properties of the cellular microenvironment modulate the growth of tumour spheroids. Based on the composition of the extracellular matrix, its stiffness and architecture can significantly vary, subsequently influencing cell movement and tumour growth. However...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968691/ https://www.ncbi.nlm.nih.gov/pubmed/33635856 http://dx.doi.org/10.1371/journal.pcbi.1008764 |