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Structural analysis of viral ExoN domains reveals polyphyletic hijacking events

Nidoviruses and arenaviruses are the only known RNA viruses encoding a 3’-5’ exonuclease domain (ExoN). The proofreading activity of the ExoN domain has played a key role in the growth of nidoviral genomes, while in arenaviruses this domain partakes in the suppression of the host innate immune signa...

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Detalles Bibliográficos
Autores principales: Cruz-González, Adrián, Muñoz-Velasco, Israel, Cottom-Salas, Wolfgang, Becerra, Arturo, Campillo-Balderas, José A., Hernández-Morales, Ricardo, Vázquez-Salazar, Alberto, Jácome, Rodrigo, Lazcano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968707/
https://www.ncbi.nlm.nih.gov/pubmed/33730017
http://dx.doi.org/10.1371/journal.pone.0246981