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HPLC method development/validation and skin diffusion study of caffeine, methyl paraben and butyl paraben as skin–diffusing model drugs

The focus of this research was to develop and validate a suitable HPLC method, which allows simultaneous determination of three proposed skin model penetrants to investigate the percutaneous diffusion behavior of their combination: caffeine, methyl paraben and butyl paraben. These penetrants were se...

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Detalles Bibliográficos
Autores principales: Mansour, Randa S. H., Hamdan, Imad I., Salem, Mutaz S. H., Khalil, Enam A., Sallam, ALSayed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968716/
https://www.ncbi.nlm.nih.gov/pubmed/33730060
http://dx.doi.org/10.1371/journal.pone.0247879