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Breast cancer–secreted factors perturb murine bone growth in regions prone to metastasis
Breast cancer frequently metastasizes to bone, causing osteolytic lesions. However, how factors secreted by primary tumors affect the bone microenvironment before the osteolytic phase of metastatic tumor growth remains unclear. Understanding these changes is critical as they may regulate metastatic...
Autores principales: | Chiou, Aaron E., Liu, Chuang, Moreno-Jiménez, Inés, Tang, Tengteng, Wagermaier, Wolfgang, Dean, Mason N., Fischbach, Claudia, Fratzl, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968847/ https://www.ncbi.nlm.nih.gov/pubmed/33731354 http://dx.doi.org/10.1126/sciadv.abf2283 |
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