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Theory of Allosteric Regulation in Hsp70 Molecular Chaperones
Heat-shock proteins of 70 kDa (Hsp70s) are ubiquitous molecular chaperones that function in protein folding as well as other vital cellular processes. They bind and hydrolyze ATP in a nucleotide-binding domain (NBD) to control the binding and release of client polypeptides in a substrate-binding dom...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cambridge University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968864/ https://www.ncbi.nlm.nih.gov/pubmed/33738455 http://dx.doi.org/10.1017/qrd.2020.10 |