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Lysyl oxidase inhibition in primary myelofibrosis: A renewed strategy

Primary myelofibrosis (PMF) is a type of myeloproliferative neoplasm (MPN) that portends a poor prognosis and has limited options for treatment. PMF is often driven by clonal mutations in one of three genes that regulate the JAK-STAT signaling pathway, leading to hyperactivation of this signaling pa...

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Detalles Bibliográficos
Autores principales: Piasecki, Andrew, Leiva, Orly, Ravid, Katya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968867/
https://www.ncbi.nlm.nih.gov/pubmed/33738462
http://dx.doi.org/10.46439/stemcell.1.005