Local genetic context shapes the function of a gene regulatory network

Gene expression levels are influenced by multiple coexisting molecular mechanisms. Some of these interactions such as those of transcription factors and promoters have been studied extensively. However, predicting phenotypes of gene regulatory networks (GRNs) remains a major challenge. Here, we use...

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Detalles Bibliográficos
Autores principales: Nagy-Staron, Anna, Tomasek, Kathrin, Caruso Carter, Caroline, Sonnleitner, Elisabeth, Kavčič, Bor, Paixão, Tiago, Guet, Calin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968929/
https://www.ncbi.nlm.nih.gov/pubmed/33683203
http://dx.doi.org/10.7554/eLife.65993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968929/
https://www.ncbi.nlm.nih.gov/pubmed/33683203
http://dx.doi.org/10.7554/eLife.65993

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