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Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects

PURPOSE: To investigate the efficacy of cordycepin, an adenosine analogue, on prevention of esophageal damage and stricture formation due to esophageal caustic burns in rat model comparing with prednisolone. METHODS: Caustic esophageal burn was introduced by 37.5% of NaOH to distal esophagus. Thirty...

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Detalles Bibliográficos
Autores principales: Ercan, Gulcin, Altinel, Yuksel, Karagulle, Onur Olgac, Yiğitbaş, Hakan, Hacım, Nadir Adnan, Meriç, Serhat, Buğdaycı, Nihat, Tartar, Rumeysa Ilbar, Biltekin, Burcu, Yavuz, Erkan, Gulcicek, Osman Bilgin, Solmaz, Ali, Çelik, Atilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968946/
https://www.ncbi.nlm.nih.gov/pubmed/33729331
http://dx.doi.org/10.1590/ACB360302