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FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo

RNA–protein interaction is central to post-transcriptional gene regulation. Identification of RNA-binding proteins relies mainly on UV-induced crosslinking (UVX) followed by the enrichment of RNA–protein conjugates and LC-MS/MS analysis. However, UVX has limited applicability in tissues of multicell...

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Detalles Bibliográficos
Autores principales: Na, Yongwoo, Kim, Hyunjoon, Choi, Yeon, Shin, Sanghee, Jung, Jae Hun, Kwon, S Chul, Kim, V Narry, Kim, Jong-Seo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968992/
https://www.ncbi.nlm.nih.gov/pubmed/33332543
http://dx.doi.org/10.1093/nar/gkaa1194