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FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo
RNA–protein interaction is central to post-transcriptional gene regulation. Identification of RNA-binding proteins relies mainly on UV-induced crosslinking (UVX) followed by the enrichment of RNA–protein conjugates and LC-MS/MS analysis. However, UVX has limited applicability in tissues of multicell...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968992/ https://www.ncbi.nlm.nih.gov/pubmed/33332543 http://dx.doi.org/10.1093/nar/gkaa1194 |