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Smart-ORF: a single-molecule method for accessing ribosome dynamics in both upstream and main open reading frames
Upstream open reading frame (uORF) translation disrupts scanning 43S flux on mRNA and modulates main open reading frame (mORF) translation efficiency. Current tools, however, have limited access to ribosome dynamics in both upstream and main ORFs of an mRNA. Here, we develop a new two-color in vitro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969011/ https://www.ncbi.nlm.nih.gov/pubmed/33330921 http://dx.doi.org/10.1093/nar/gkaa1185 |