A suppressor tRNA-mediated feedforward loop eliminates leaky gene expression in bacteria

Ligand-inducible genetic systems are the mainstay of synthetic biology, allowing gene expression to be controlled by the presence of a small molecule. However, ‘leaky’ gene expression in the absence of inducer remains a persistent problem. We developed a leak dampener tool that drastically reduces t...

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Detalles Bibliográficos
Autores principales: Ho, Joanne M L, Miller, Corwin A, Parks, Sydney E, Mattia, Jacob R, Bennett, Matthew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969014/
https://www.ncbi.nlm.nih.gov/pubmed/33290521
http://dx.doi.org/10.1093/nar/gkaa1179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969014/
https://www.ncbi.nlm.nih.gov/pubmed/33290521
http://dx.doi.org/10.1093/nar/gkaa1179

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