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A suppressor tRNA-mediated feedforward loop eliminates leaky gene expression in bacteria
Ligand-inducible genetic systems are the mainstay of synthetic biology, allowing gene expression to be controlled by the presence of a small molecule. However, ‘leaky’ gene expression in the absence of inducer remains a persistent problem. We developed a leak dampener tool that drastically reduces t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969014/ https://www.ncbi.nlm.nih.gov/pubmed/33290521 http://dx.doi.org/10.1093/nar/gkaa1179 |