Single bacterial resolvases first exploit, then constrain intrinsic dynamics of the Holliday junction to direct recombination

Homologous recombination forms and resolves an entangled DNA Holliday Junction (HJ) crucial for achieving genetic reshuffling and genome repair. To maintain genomic integrity, specialized resolvase enzymes cleave the entangled DNA into two discrete DNA molecules. However, it is unclear how two simil...

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Detalles Bibliográficos
Autores principales: Ray, Sujay, Pal, Nibedita, Walter, Nils G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969024/
https://www.ncbi.nlm.nih.gov/pubmed/33619520
http://dx.doi.org/10.1093/nar/gkab096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969024/
https://www.ncbi.nlm.nih.gov/pubmed/33619520
http://dx.doi.org/10.1093/nar/gkab096

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