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Single bacterial resolvases first exploit, then constrain intrinsic dynamics of the Holliday junction to direct recombination
Homologous recombination forms and resolves an entangled DNA Holliday Junction (HJ) crucial for achieving genetic reshuffling and genome repair. To maintain genomic integrity, specialized resolvase enzymes cleave the entangled DNA into two discrete DNA molecules. However, it is unclear how two simil...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969024/ https://www.ncbi.nlm.nih.gov/pubmed/33619520 http://dx.doi.org/10.1093/nar/gkab096 |