Inhibition of PTEN Ameliorates Secondary Hippocampal Injury and Cognitive Deficits after Intracerebral Hemorrhage: Involvement of AKT/FoxO3a/ATG-Mediated Autophagy

Spontaneous intracerebral hemorrhage (ICH) commonly causes secondary hippocampal damage and delayed cognitive impairments, but the mechanisms remain elusive. Here, we sought to identify the molecular mechanisms underlying these hemorrhagic outcomes in a rat autologous blood model of ICH. First, a si...

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Detalles Bibliográficos
Autores principales: Zhao, Manman, Gao, Junling, Cui, Changmeng, Zhang, Yanan, Jiang, Xiaohua, Cui, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969103/
https://www.ncbi.nlm.nih.gov/pubmed/33777313
http://dx.doi.org/10.1155/2021/5472605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969103/
https://www.ncbi.nlm.nih.gov/pubmed/33777313
http://dx.doi.org/10.1155/2021/5472605

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