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Islet Transplantation Reverses Podocyte Injury in Diabetic Nephropathy or Induced by High Glucose via Inhibiting RhoA/ROCK/NF-κB Signaling Pathway

OBJECTIVE: Abnormal signaling pathways play a crucial role in the mechanisms of podocyte injury in diabetic nephropathy. They also affect the recovery of podocytes after islet transplantation (IT). However, the specific signaling abnormalities that affect the therapeutic effect of IT on podocytes re...

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Detalles Bibliográficos
Autores principales: Huang, Chongchu, Zhou, Yi, Huang, Hongjian, Zheng, Yushu, Kong, Lijun, Zhang, Hewei, Zhang, Yan, Wang, Hongwei, Yang, Mei, Xu, Xiaona, Chen, Bicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969114/
https://www.ncbi.nlm.nih.gov/pubmed/33778085
http://dx.doi.org/10.1155/2021/9570405