Development of a Gestational and Lactational Physiologically Based Pharmacokinetic (PBPK) Model for Perfluorooctane Sulfonate (PFOS) in Rats and Humans and Its Implications in the Derivation of Health-Based Toxicity Values

BACKGROUND: There is a great concern on potential adverse effects of exposure to perfluorooctane sulfonate (PFOS) in sensitive subpopulations, such as pregnant women, fetuses, and neonates, due to its reported transplacental and lactational transfer and reproductive and developmental toxicities in a...

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Detalles Bibliográficos
Autores principales: Chou, Wei-Chun, Lin, Zhoumeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969127/
https://www.ncbi.nlm.nih.gov/pubmed/33730865
http://dx.doi.org/10.1289/EHP7671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969127/
https://www.ncbi.nlm.nih.gov/pubmed/33730865
http://dx.doi.org/10.1289/EHP7671

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