Zika Virus Envelope Domain III Recombinant Protein Delivered With Saponin-Based Nanoadjuvant From Quillaja brasiliensis Enhances Anti-Zika Immune Responses, Including Neutralizing Antibodies and Splenocyte Proliferation

Nanoadjuvants that combine immunostimulatory properties and delivery systems reportedly bestow major improvements on the efficacy of recombinant, protein-based vaccines. Among these, self-assembled micellar formulations named ISCOMs (immune stimulating complexes) show a great ability to trigger powe...

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Detalles Bibliográficos
Autores principales: Cibulski, Samuel, Varela, Ana Paula Muterle, Teixeira, Thais Fumaco, Cancela, Martín Pablo, Sesterheim, Patrícia, Souza, Diogo Onofre, Roehe, Paulo Michel, Silveira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969523/
https://www.ncbi.nlm.nih.gov/pubmed/33746970
http://dx.doi.org/10.3389/fimmu.2021.632714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969523/
https://www.ncbi.nlm.nih.gov/pubmed/33746970
http://dx.doi.org/10.3389/fimmu.2021.632714

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