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Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depression

Ketamine produces a rapid antidepressant response in over 50% of adults with treatment-resistant depression. A long infusion of ketamine may provide durable remission of depressive symptoms, but the safety, efficacy, and neurobiological correlates are unknown. In this open-label, proof-of-principle...

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Detalles Bibliográficos
Autores principales: Siegel, Joshua S., Palanca, Ben J. A., Ances, Beau M., Kharasch, Evan D., Schweiger, Julie A., Yingling, Michael D., Snyder, Abraham Z., Nicol, Ginger E., Lenze, Eric J., Farber, Nuri B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969576/
https://www.ncbi.nlm.nih.gov/pubmed/33483802
http://dx.doi.org/10.1007/s00213-021-05762-6