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Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depression
Ketamine produces a rapid antidepressant response in over 50% of adults with treatment-resistant depression. A long infusion of ketamine may provide durable remission of depressive symptoms, but the safety, efficacy, and neurobiological correlates are unknown. In this open-label, proof-of-principle...
Autores principales: | Siegel, Joshua S., Palanca, Ben J. A., Ances, Beau M., Kharasch, Evan D., Schweiger, Julie A., Yingling, Michael D., Snyder, Abraham Z., Nicol, Ginger E., Lenze, Eric J., Farber, Nuri B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969576/ https://www.ncbi.nlm.nih.gov/pubmed/33483802 http://dx.doi.org/10.1007/s00213-021-05762-6 |
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