Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples

Mucus hypersecretion contributes to lung function impairment observed in COPD (chronic obstructive pulmonary disease), a tobacco smoking-related disease. A detailed mucus hypersecretion adverse outcome pathway (AOP) has been constructed from literature reviews, experimental and clinical data, mappin...

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Detalles Bibliográficos
Autores principales: Minet, Emmanuel, Haswell, Linsey E., Corke, Sarah, Banerjee, Anisha, Baxter, Andrew, Verrastro, Ivan, De Abreu e Lima, Francisco, Jaunky, Tomasz, Santopietro, Simone, Breheny, Damien, Gaça, Marianna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969622/
https://www.ncbi.nlm.nih.gov/pubmed/33731770
http://dx.doi.org/10.1038/s41598-021-85345-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969622/
https://www.ncbi.nlm.nih.gov/pubmed/33731770
http://dx.doi.org/10.1038/s41598-021-85345-9

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