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The role of PKM2 nuclear translocation in the constant activation of the NF-κB signaling pathway in cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs) play critical roles in cancer progression by regulating tumor cell proliferation, angiogenesis, and metastasis. Recent studies demonstrated that CAFs induce inhibitory immune cell infiltration and chemotherapy resistance in gastric cancer by activating the NF-κB...

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Detalles Bibliográficos
Autores principales: Gu, Junjie, Li, Xuechun, Zhao, Lin, Yang, Ying, Xue, Chunling, Gao, Yang, Li, Jing, Han, Qin, Sun, Zhao, Bai, Chunmei, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969736/
https://www.ncbi.nlm.nih.gov/pubmed/33731686
http://dx.doi.org/10.1038/s41419-021-03579-x