Cargando…
The role of PKM2 nuclear translocation in the constant activation of the NF-κB signaling pathway in cancer-associated fibroblasts
Cancer-associated fibroblasts (CAFs) play critical roles in cancer progression by regulating tumor cell proliferation, angiogenesis, and metastasis. Recent studies demonstrated that CAFs induce inhibitory immune cell infiltration and chemotherapy resistance in gastric cancer by activating the NF-κB...
Autores principales: | Gu, Junjie, Li, Xuechun, Zhao, Lin, Yang, Ying, Xue, Chunling, Gao, Yang, Li, Jing, Han, Qin, Sun, Zhao, Bai, Chunmei, Zhao, Robert Chunhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969736/ https://www.ncbi.nlm.nih.gov/pubmed/33731686 http://dx.doi.org/10.1038/s41419-021-03579-x |
Ejemplares similares
-
HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210
por: Yang, Ying, et al.
Publicado: (2021) -
Cancer-Associated Fibroblasts Promote the Upregulation of PD-L1 Expression Through Akt Phosphorylation in Colorectal Cancer
por: Gao, Yang, et al.
Publicado: (2021) -
Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis
por: Xue, Chunling, et al.
Publicado: (2022) -
DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2
por: Zhao, Gang, et al.
Publicado: (2022) -
TGF-βRII regulates glucose metabolism in oral cancer-associated fibroblasts via promoting PKM2 nuclear translocation
por: Wu, Fanglong, et al.
Publicado: (2022)