Mechanical stress determines the configuration of TGFβ activation in articular cartilage

Our incomplete understanding of osteoarthritis (OA) pathogenesis has significantly hindered the development of disease-modifying therapy. The functional relationship between subchondral bone (SB) and articular cartilage (AC) is unclear. Here, we found that the changes of SB architecture altered the...

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Detalles Bibliográficos
Autores principales: Zhen, Gehua, Guo, Qiaoyue, Li, Yusheng, Wu, Chuanlong, Zhu, Shouan, Wang, Ruomei, Guo, X. Edward, Kim, Byoung Choul, Huang, Jessie, Hu, Yizhong, Dan, Yang, Wan, Mei, Ha, Taekjip, An, Steven, Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969741/
https://www.ncbi.nlm.nih.gov/pubmed/33731712
http://dx.doi.org/10.1038/s41467-021-21948-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969741/
https://www.ncbi.nlm.nih.gov/pubmed/33731712
http://dx.doi.org/10.1038/s41467-021-21948-0

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