Mechanical stress determines the configuration of TGFβ activation in articular cartilage

Our incomplete understanding of osteoarthritis (OA) pathogenesis has significantly hindered the development of disease-modifying therapy. The functional relationship between subchondral bone (SB) and articular cartilage (AC) is unclear. Here, we found that the changes of SB architecture altered the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhen, Gehua, Guo, Qiaoyue, Li, Yusheng, Wu, Chuanlong, Zhu, Shouan, Wang, Ruomei, Guo, X. Edward, Kim, Byoung Choul, Huang, Jessie, Hu, Yizhong, Dan, Yang, Wan, Mei, Ha, Taekjip, An, Steven, Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969741/
https://www.ncbi.nlm.nih.gov/pubmed/33731712
http://dx.doi.org/10.1038/s41467-021-21948-0

Ejemplares similares

Ejemplares similares