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Prioritization of schizophrenia risk genes from GWAS results by integrating multi-omics data

Schizophrenia (SCZ) is a polygenic disease with a heritability approaching 80%. Over 100 SCZ-related loci have so far been identified by genome-wide association studies (GWAS). However, the risk genes associated with these loci often remain unknown. We present a new risk gene predictor, rGAT-omics,...

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Detalles Bibliográficos
Autores principales: He, Dan, Fan, Cong, Qi, Mengling, Yang, Yuedong, Cooper, David N., Zhao, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969765/
https://www.ncbi.nlm.nih.gov/pubmed/33731678
http://dx.doi.org/10.1038/s41398-021-01294-x