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Tumor-secreted exosomal Wnt2B activates fibroblasts to promote cervical cancer progression

The activation of stromal fibroblasts into cancer-associated fibroblasts (CAFs) has been suggested to promote primary tumor growth and progression; however, the mechanisms underlying the crosstalk between tumors and fibroblasts that drives stromal heterogeneity remain unknown. Here, we show that hig...

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Detalles Bibliográficos
Autores principales: Liang, Luo-Jiao, Yang, Yang, Wei, Wen-Fei, Wu, Xiang-Guang, Yan, Rui-Ming, Zhou, Chen-Fei, Chen, Xiao-Jing, Wu, Sha, Wang, Wei, Fan, Liang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969781/
https://www.ncbi.nlm.nih.gov/pubmed/33731705
http://dx.doi.org/10.1038/s41389-021-00319-w