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Downregulation of Macrophage-Specific Act-1 Intensifies Periodontitis and Alveolar Bone Loss Possibly via TNF/NF-κB Signaling

Periodontitis is a chronic inflammatory oral disease that affects almost half of the adult population. NF-κB activator 1 (Act1) is mainly expressed in immune cells, including macrophages, and modulates immune cells’ function to regulate inflammation in inflammatory diseases. Macrophages play a vital...

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Detalles Bibliográficos
Autores principales: Pathak, Janak L., Fang, Ying, Chen, Yunxin, Ye, Zhitong, Guo, Xueqi, Yan, Yongyong, Zha, Jun, Liang, Dongliang, Ke, Xiuxian, Yang, Luxi, Zhong, Wenchao, Wang, Lijing, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969798/
https://www.ncbi.nlm.nih.gov/pubmed/33748112
http://dx.doi.org/10.3389/fcell.2021.628139