CDK9 Inhibitor Induces the Apoptosis of B-Cell Acute Lymphocytic Leukemia by Inhibiting c-Myc-Mediated Glycolytic Metabolism

B-cell acute lymphocytic leukemia (B-ALL), a common blood cancer in children, leads to high mortality. Cyclin-dependent kinase 9 inhibitor (CDK9i) effectively attenuates acute myeloid leukemia and chronic lymphoblastic leukemia by inducing apoptosis and inhibiting cell proliferation. However, the ef...

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Detalles Bibliográficos
Autores principales: Huang, Wen-Li, Abudureheman, Tuersunayi, Xia, Jing, Chu, Lei, Zhou, Hang, Zheng, Wei-Wei, Zhou, Neng, Shi, Rong-Yi, Li, Ming-Hao, Zhu, Jian-Min, Qing, Kai, Ji, Chao, Liang, Kai-Wei, Guo, Sa, Yin, Gang, Duan, Cai-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969802/
https://www.ncbi.nlm.nih.gov/pubmed/33748130
http://dx.doi.org/10.3389/fcell.2021.641271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969802/
https://www.ncbi.nlm.nih.gov/pubmed/33748130
http://dx.doi.org/10.3389/fcell.2021.641271

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