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The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy

Narcolepsy is a sleep disorder caused by selective death of the orexin neurons that often begins in childhood. Orexin neuron loss disinhibits REM sleep during the active period and produces cataplexy, episodes of paralysis during wakefulness. Cataplexy is often worse when narcolepsy develops in chil...

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Detalles Bibliográficos
Autores principales: Coffey, Alissa A., Joyal, Adam A., Yamanaka, Akihiro, Scammell, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969886/
https://www.ncbi.nlm.nih.gov/pubmed/33746708
http://dx.doi.org/10.3389/fnins.2021.644757