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A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques

The deployment of a vaccine that limits transmission and disease likely will be required to end the coronavirus disease 2019 (COVID-19) pandemic. We recently described the protective activity of an intranasally administered chimpanzee adenovirus-vectored vaccine encoding a pre-fusion stabilized spik...

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Detalles Bibliográficos
Autores principales: Hassan, Ahmed O., Feldmann, Friederike, Zhao, Haiyan, Curiel, David T., Okumura, Atsushi, Tang-Huau, Tsing-Lee, Case, James Brett, Meade-White, Kimberly, Callison, Julie, Chen, Rita E., Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana P., Fremont, Daved H., Feldmann, Heinz, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969912/
https://www.ncbi.nlm.nih.gov/pubmed/33754147
http://dx.doi.org/10.1016/j.xcrm.2021.100230