Cargando…
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice
GPR37 was discovered more than two decades ago, but its biological functions remain poorly understood. Here we report a protective role of GPR37 in multiple models of infection and sepsis. Mice lacking Gpr37 exhibited increased death and/or hypothermia following challenge by lipopolysaccharide (LPS)...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969930/ https://www.ncbi.nlm.nih.gov/pubmed/33731716 http://dx.doi.org/10.1038/s41467-021-21940-8 |