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BNST specific mGlu5 receptor knockdown regulates sex-dependent expression of negative affect produced by adolescent ethanol exposure and adult stress

Adolescent alcohol use is one of the strongest predictors for the development of an alcohol use disorder (AUD). Notably, this period of risk coincides with the development of affective disorders, which disproportionately impact and drive problematic drinking behavior in women. Stress is a particular...

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Detalles Bibliográficos
Autores principales: Kasten, Chelsea R., Holmgren, Eleanor B., Lerner, Mollie R., Wills, Tiffany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969933/
https://www.ncbi.nlm.nih.gov/pubmed/33731684
http://dx.doi.org/10.1038/s41398-021-01285-y