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T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance

Estrogen deficiency is one of the most frequent causes of osteoporosis in postmenopausal women. Under chronic inflammatory conditions caused by estrogen deficiency, activated T cells contribute to elevated levels of proinflammatory cytokines, impaired osteogenic differentiation capabilities of bone...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoshan, Zhou, Fuxing, Yuan, Pingyun, Dou, Geng, Liu, Xuemei, Liu, Siying, Wang, Xiangdong, Jin, Ronghua, Dong, Yan, Zhou, Jun, Lv, Yajie, Deng, Zhihong, Liu, Shiyu, Chen, Xin, Han, Ying, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970013/
https://www.ncbi.nlm.nih.gov/pubmed/33778195
http://dx.doi.org/10.1016/j.bioactmat.2021.02.034