PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNF a-CX3CR1 pathway

Previous studies have suggested that pyrrolidine dithiocarbamate (PDTC), a nuclear factor κB (NF-κB) inhibitor, plays a role in deterring nerve injury-induced neuropathic pain (NP). The activation of NF-κB pathway may contribute to spinal microglial activation, CX3CR1 and tumor necrosis factor-alpha...

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Detalles Bibliográficos
Autores principales: Li, Xilei, Ye, Zhi, Guo, Qulian, Wang, E, Pan, Yundan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970247/
https://www.ncbi.nlm.nih.gov/pubmed/33728865
http://dx.doi.org/10.4081/ejh.2021.3184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970247/
https://www.ncbi.nlm.nih.gov/pubmed/33728865
http://dx.doi.org/10.4081/ejh.2021.3184

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