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PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNF a-CX3CR1 pathway
Previous studies have suggested that pyrrolidine dithiocarbamate (PDTC), a nuclear factor κB (NF-κB) inhibitor, plays a role in deterring nerve injury-induced neuropathic pain (NP). The activation of NF-κB pathway may contribute to spinal microglial activation, CX3CR1 and tumor necrosis factor-alpha...
Autores principales: | Li, Xilei, Ye, Zhi, Guo, Qulian, Wang, E, Pan, Yundan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970247/ https://www.ncbi.nlm.nih.gov/pubmed/33728865 http://dx.doi.org/10.4081/ejh.2021.3184 |
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