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Designed improvement to T-cell immunotherapy by multidimensional single cell profiling

BACKGROUND: Adoptive cell therapy based on the infusion of chimeric antigen receptor (CAR) T cells has shown remarkable efficacy for the treatment of hematologic malignancies. The primary mechanism of action of these infused T cells is the direct killing of tumor cells expressing the cognate antigen...

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Detalles Bibliográficos
Autores principales: Bandey, Irfan N, Adolacion, Jay R T, Romain, Gabrielle, Paniagua, Melisa Martinez, An, Xingyue, Saeedi, Arash, Liadi, Ivan, You, Zheng, Rajanayake, Rasindu B, Hwu, Patrick, Singh, Harjeet, Cooper, Laurence JN, Varadarajan, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970283/
https://www.ncbi.nlm.nih.gov/pubmed/33722906
http://dx.doi.org/10.1136/jitc-2020-001877