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The Effects of Apelin and Elabela Ligands on Apelin Receptor Distinct Signaling Profiles
Apelin and Elabela are endogenous peptide ligands for Apelin receptor (APJ), a widely expressed G protein-coupled receptor. They constitute a spatiotemporal dual ligand system to control APJ signal transduction and function. We investigated the effects of Apelin-13, pGlu(1)-apelin-13, Apelin-17, Ape...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970304/ https://www.ncbi.nlm.nih.gov/pubmed/33746758 http://dx.doi.org/10.3389/fphar.2021.630548 |