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IL-6 inhibition in the treatment of COVID-19: A meta-analysis and meta-regression

OBJECTIVES: Multiple RCTs of interleukin-6 (IL-6) inhibitors in COVID-19 have been published, with conflicting conclusions. We performed a meta-analysis to assess the impact of IL-6 inhibition on mortality from COVID-19, utilising meta-regression to explore differences in study results. METHODS: Sys...

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Detalles Bibliográficos
Autores principales: Tharmarajah, Emmanuel, Buazon, April, Patel, Vishit, Hannah, Jennifer R., Adas, Maryam, Allen, Victoria B., Bechman, Katie, Clarke, Benjamin D., Nagra, Deepak, Norton, Sam, Russell, Mark D., Rutherford, Andrew I., Yates, Mark, Galloway, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970418/
https://www.ncbi.nlm.nih.gov/pubmed/33745918
http://dx.doi.org/10.1016/j.jinf.2021.03.008