Cargando…

Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein

[Image: see text] Serine proteases neutrophil elastase (NE), protease 3 (PR3), cathepsin G (CatG), and neutrophil serine protease 4 (NSP4) are released by activated neutrophils swarming around the place of pathogen invasion to provoke an immune response. However, uncontrolled proteolytic activity of...

Descripción completa

Detalles Bibliográficos
Autores principales: Mustafa, Zhadyra, Zhanapiya, Anuar, Kalbacher, Hubert, Burster, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970549/
https://www.ncbi.nlm.nih.gov/pubmed/33748632
http://dx.doi.org/10.1021/acsomega.1c00363