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Effect of Disease State on the Pharmacokinetics of Bedaquiline in Renal-Impaired and Diabetic Rats

[Image: see text] Bedaquiline (TMC-207) is a key anti-tubercular drug to fight against multidrug resistance tuberculosis. Little information is available till date on the impact of any disease state toward its pharmacokinetic behavior. The present research work aimed to investigate the effect of ren...

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Detalles Bibliográficos
Autores principales: Gour, Abhishek, Dogra, Ashish, Sharma, Sumit, Wazir, Priya, Nandi, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970569/
https://www.ncbi.nlm.nih.gov/pubmed/33748607
http://dx.doi.org/10.1021/acsomega.0c06165