Supramolecular Self-Assembly Built by Weak Hydrogen, Chalcogen, and Unorthodox Nonbonded Motifs in 4-(4-Chlorophenyl)-3-[(4-fluorobenzyl)sulfanyl]-5-(thiophen-2-yl)-4H-1,2,4-triazole, a Selective COX-2 Inhibitor: Insights from X-ray and Theoretical Studies

[Image: see text] A selective triazole-based COX-2 inhibitor, 4-(4-chlorophenyl)-3-[(4-fluorobenzyl)sulfanyl]-5-(thiophen-2-yl)-4H-1,2,4-triazole, C(19)H(13)ClFN(3)S(2), has been synthesized, and its crystal structure was determined at 150 K. Single-crystal X-ray diffraction analysis revealed that t...

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Detalles Bibliográficos
Autores principales: Al-Wahaibi, Lamya H., Rahul, Bavanandan, Mohamed, Ahmed A. B., Abdelbaky, Mohammed S. M., Garcia-Granda, Santiago, El-Emam, Ali A., Percino, M. Judith, Thamotharan, Subbiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970574/
https://www.ncbi.nlm.nih.gov/pubmed/33748613
http://dx.doi.org/10.1021/acsomega.0c06287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970574/
https://www.ncbi.nlm.nih.gov/pubmed/33748613
http://dx.doi.org/10.1021/acsomega.0c06287

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