Targeted inhibition of β-catenin alleviates airway inflammation and remodeling in asthma via modulating the profibrotic and anti-inflammatory actions of transforming growth factor-β(1)

BACKGROUND: TGF-β(1) is a key cytokine involved in both airway inflammation and airway remodeling in asthma because of its anti-inflammatory and profibrotic effect. In our previous study, we found that knockdown of cytosolic β-catenin alleviated the profibrogenic effect of TGF-β(1) without influenci...

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Detalles Bibliográficos
Autores principales: Huo, Rujie, Tian, Xinli, Chang, Qin, Liu, Dai, Wang, Chen, Bai, Jingcui, Wang, Runjuan, Zheng, Guoping, Tian, Xinrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970683/
https://www.ncbi.nlm.nih.gov/pubmed/33530899
http://dx.doi.org/10.1177/1753466620981858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970683/
https://www.ncbi.nlm.nih.gov/pubmed/33530899
http://dx.doi.org/10.1177/1753466620981858

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