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Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils

Anaplasma phagocytophilum is a tick-transmitted obligate intracellular Gram-negative bacterium that replicates in neutrophils. It elicits febrile disease in humans and in animals. In a mouse model, elimination of A. phagocytophilum required CD4(+) T cells, but was independent of IFN-γ and other clas...

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Detalles Bibliográficos
Autores principales: Müller, Beate J., Westheider, Arne, Birkner, Katharina, Seelig, Birte, Kirschnek, Susanne, Bogdan, Christian, von Loewenich, Friederike D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970703/
https://www.ncbi.nlm.nih.gov/pubmed/33747981
http://dx.doi.org/10.3389/fcimb.2021.627630