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Variability in mRNA translation: a random matrix theory approach

The rate of mRNA translation depends on the initiation, elongation, and termination rates of ribosomes along the mRNA. These rates depend on many “local” factors like the abundance of free ribosomes and tRNA molecules in the vicinity of the mRNA molecule. All these factors are stochastic and their e...

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Detalles Bibliográficos
Autores principales: Margaliot, Michael, Huleihel, Wasim, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970873/
https://www.ncbi.nlm.nih.gov/pubmed/33674667
http://dx.doi.org/10.1038/s41598-021-84738-0