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Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption

Emergent evidence demonstrates that excessive consumption of high fat and high sugar (HFHS) diets has negative consequences on hippocampal and prefrontal cortex (PFC) function. Moreover, the delayed maturation of the PFC including the late development of parvalbumin-expressing (PV) interneurons and...

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Detalles Bibliográficos
Autores principales: Reichelt, Amy C., Lemieux, Claire A., Princz-Lebel, Oren, Singh, Ashmita, Bussey, Timothy J., Saksida, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970944/
https://www.ncbi.nlm.nih.gov/pubmed/33692414
http://dx.doi.org/10.1038/s41598-021-85092-x