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Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes

Tissue-specific autoimmune diseases are driven by activation of diverse immune cells in the target organs. However, the molecular signatures of immune cell populations over time in an autoimmune process remain poorly defined. Using single-cell RNA sequencing, we performed an unbiased examination of...

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Detalles Bibliográficos
Autores principales: Zakharov, Pavel N., Hu, Hao, Wan, Xiaoxiao, Unanue, Emil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971127/
https://www.ncbi.nlm.nih.gov/pubmed/32251514
http://dx.doi.org/10.1084/jem.20192362