Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions

Invariant natural killer T (iNKT) cells acquire effector functions during development by mechanisms that remain poorly understood. Here, we show that the Hippo kinases Mst1 and Mst2 act as molecular rheostats for the terminal maturation and effector differentiation programs of iNKT cells. Loss of Ms...

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Detalles Bibliográficos
Autores principales: Raynor, Jana L., Liu, Chaohong, Dhungana, Yogesh, Guy, Cliff, Chapman, Nicole M., Shi, Hao, Neale, Geoffrey, Sesaki, Hiromi, Chi, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971129/
https://www.ncbi.nlm.nih.gov/pubmed/32289155
http://dx.doi.org/10.1084/jem.20191157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971129/
https://www.ncbi.nlm.nih.gov/pubmed/32289155
http://dx.doi.org/10.1084/jem.20191157

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